The Longevity Medical
Research Fund

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Recommended reading:
A newly-published call-to-arms and technical exposition on the SENS approach to age-related disease
An early study of one of the seven targets of SENS research
What to do in the meantime:
Full of diet and lifestyle tips based on current science, to preserve your health until better technology is developed

Only 7 Pathogenic Age-related Precursors: Cell Death


Two of the seven early precursors of age-related pathology are cells that are helpful but die and cells that are harmful but don't.




The former is the object of growth factors and stem cell research. These don't fall under the umbrella of LMRF's beneficiaries, since they are pursued on such a large scale already.

The latter is characterized by three kinds of cells:
  • visceral fat cells (with its relation to diabetes);
  • senescent cells (half-dead dysfunctional cells, many of which spew toxins); and,
  • certain kinds of immune cells (which crowd out more functional immune cells).
The proposed strategies for killing these cells would take advantage of cell surface markers to focus treatment and minimize side effects.

Note that this list doesn't include non-OXPHOS mitochondrion-dominated cells, since they would not be identifiable by surface markers.

Though surgery is a possible solution for visceral fat removal, it may be unnecessarily invasive if surface markers can be taken advantage of.